Neither MICA Nor DEPDC5 Genetic Polymorphisms Correlate with Hepatocellular Carcinoma Recurrence following Hepatectomy
Table 1
Data among HCV-positive patients who underwent hepatectomy for HCC carrying GG, GA, and AA allele at rs2596542 (MICA).
rs2596542
GG
GA
AA
value
Age (y), mean ± SD
68 ± 1
69 ± 1
72 ± 2
n.s
Sex (male/female),
21/9
18/4
11/1
n.s
Platelet count (×104/L), mean ± SD
13.1 ± 1.0
14.8 ± 1.2
13.8 ± 1.6
n.s
Total bilirubin level (mg/dL), mean ± SD
0.9 ± 0.07
0.9 ± 0.08
0.9 ± 0.1
n.s
Prothrombin time (%), mean ± SD
0/11/10
1/8/13
0/1/7
n.s
ICGR15 (%), mean ± SD
15.9 ± 1.4
16.5 ± 1.7
14.7 ± 2.3
n.s
Operative time (min), mean ± SD
369 ± 19
342 ± 23
322 ± 31
n.s
Intraoperative bleeding (mL), mean ± SD
779 ± 100
586 ± 118
617 ± 160
n.s
Maximum tumor size (cm), mean ± SD
3.7 ± 0.4
3.3 ± 0.5
3.3 ± 0.8
n.s
AFP level (ng/mL), mean (minimum–maximum)
797 (2.3–17156)
284 (2–4746)
907 (2.2–10368)
n.s
DCP level (mAU/mL), mean (minimum–maximum)
2484 (9–46561)
2710 (10–31134)
538 (9–3817)
n.s
Stage (I/II/III/IV),
7/13/9/1
3/11/8/0
1/11/0/0
n.s
Tumor differentiation (well/moderate/poorly),
5/22/3
7/13/2
3/7/2
n.s
Fibrosis stage (F0-2/F3-4),
13/17
11/11
4/8
n.s
AFP: alpha-fetoprotein, DCP: des-gamma-carboxy prothrombin, HCC: hepatocellular carcinoma, ICGR15: indocyanine green retention at 15 minutes, and n.s: not significant.
