C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation

Figure 3

Decreased caspase 3 activation after hemorrhage and resuscitation of JNK2-deficient mice. At 6 h postoperatively, caspase 3 activity was assessed after sham operation and after H/R of wildtype and JNK2-deficient (JNK2−/−)mice, as described in Section 2. 𝑃<0.05 versus wildtype, 𝑛=5 per group.