Extended Perioperative Antibiotic Coverage in Conjunction with Intraoperative Bile Cultures Decreases Infectious Complications after Pancreaticoduodenectomy
Table 1
Postoperative events and their description.
Bacteremia
Blood culture proven bacteremia in a patient within 30 days of surgery.
Wound infection/dehiscence
Both superficial and deep surgical site infections, and/or wound dehiscence, diagnosed by laboratory confirmation or by attending physician within 30 days of surgery.
Organ/space infections
Intra-abdominal/solid organ intraparenchymal fluid collection, with purulent drainage from a drain or radiographic evidence with FNA sampling all confirmed by laboratory, presenting within 30 days of surgery.
Readmissions
Any in-patient admission to the same or different hospital for adverse events related to PD, within 30 days of surgery.
Reoperation
Procedures under general, local, spinal, or epidural anesthesia including wound debridement, in-patient I&D, IR drainage, or outpatient surgery for adverse events related to PD within 30 days of surgery.
Anastomotic leak
Any fluid collection or drain output with amylase content 3x the serum level or total bilirubin > 5 mg/dL above the patient’s serum bilirubin was considered a leak, regardless of daily output.