Nonoperative Management May Be a Viable Approach to Plexiform Neurofibroma of the Porta Hepatis in Patients with Neurofibromatosis-1

Figure 3

(a) Gross morphology of “Mass in Gallbladder.” Note the lobulated and nodular overall surface resembling a “bag of worms.” The mass measured in total 3.2 × 2.2 × 1.3 cm. (b) Plexiform neurofibroma involving the muscularis propria of the gallbladder wall (H&E, 200x). (c) Higher magnification highlights the loosely arranged spindle shaped cells of plexiform neurofibroma with peripheral entrapment of native ganglion cells (H&E, 400x). (d) Plexiform neurofibroma residing within the fibrofatty tissue adjacent to the gallbladder. (H&E, 200x) (inset) plexiform neurofibroma showing typical histologic findings with loosely arranged comma-shaped nuclei in a myxoid stroma (H&E, 600x).

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