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Infectious Diseases in Obstetrics and Gynecology
Volume 3, Issue 3, Pages 119-122
Brief Report

Pilot Study to Evaluate the Appropriate Management of Patients With Coexistent Bacterial Vaginosis and Cervicitis

1Chicago Department of Health, Chicago, IL, USA
2Medicine/Infectious Diseases Northwestern University Medical School, Chicago, IL, USA
3University of Alabama at Birmingham, 229 Tinsley Harrison Tower, 1900 University Boulevard, Birmingham 35294-0006, AL, USA

Received 19 June 1995; Accepted 17 August 1995

Copyright © 1995 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A pilot study was performed to obtain preliminary data regarding the need for targeted therapy of bacterial vaginosis (BV) when it accompanies clinically defined cervicitis. Specifically, women attending a sexually transmitted disease (STD) clinic with clinically defined BV and cervicitis were treated in the first phase of the study with doxycycline alone. In phase II, the patients received doxycycline and concomitant intravaginal metronidazole gel. All patients were reexamined 3–4 weeks after therapy. Persistence of BV occurred in 18/19 (95%) of women in phase I vs. 1/7 (14%) of women in phase II (P < 0.001). We concluded that, in women with coexistent clinically defined cervicitis and BV, the treatment of cervicitis does not result in a normalization of the vaginal flora.