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Infectious Diseases in Obstetrics and Gynecology
Volume 4, Issue 4, Pages 239-242
Obstetrics Case Report

Treatment of Recurrent Eczema Herpeticum in Pregnancy With Acyclovir

1Division of Maternal-Fetal Medicine, Abington Memorial Hospital, Abington, PA 19001, USA
2Division of Maternal-Fetal Medicine, State University of New York at Stony Brook, Stony Brook, NY, USA

Received 15 April 1996; Accepted 8 July 1996

Copyright © 1996 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background: Eczema herpeticum is an uncommon manifestation of an infection with herpes simplex virus (HSV). The disease is primarily seen in patients with histories of atopic eczema. Eczema herpeticum may be a life-threatening illness, but the mortality is felt to be <10% with modern antiviral and antibacterial agents. The use of acyclovir for other viral infections secondary to herpesvirus in pregnancy has been well documented. The authors now present a case report of eczema herpeticum treated with acyclovir during pregnancy.

Case: A patient with a history of eczema herpeticum presented in pregnancy with a recurrence. She was successfully treated with intravenous (IV) acyclovir with good maternal and fetal outcome.

Conclusion: Acyclovir may be utilized in pregnancy for several manifestations of HSV including eczema herpeticum.