Infectious Diseases in Obstetrics and Gynecology

Infectious Diseases in Obstetrics and Gynecology / 2006 / Article

Clinical Study | Open Access

Volume 2006 |Article ID 073073 | https://doi.org/10.1155/IDOG/2006/73073

R. Sinan Karadeniz, Ozlem Ozdegirmenci, M. Metin Altay, Ayse Solaroglu, Serdar Dilbaz, Nedret Hızel, Ali Haberal, "Helicobacter pylori Seropositivity and Stool Antigen in Patients With Hyperemesis Gravidarum", Infectious Diseases in Obstetrics and Gynecology, vol. 2006, Article ID 073073, 3 pages, 2006. https://doi.org/10.1155/IDOG/2006/73073

Helicobacter pylori Seropositivity and Stool Antigen in Patients With Hyperemesis Gravidarum

Received28 Apr 2005
Revised30 Apr 2005
Accepted08 Dec 2005
Published22 Feb 2006

Abstract

The objective of this paper is to investigate whether Helicobacter pylori is an etiologic factor in hyperemesis gravidarum. Thirty one patients with hyperemesis gravidarum and twenty nine pregnant controls without hyperemesis gravidarum were included in this prospective study. All pregnant women were examined both for Helicobacter pylori serum immunoglobulin G antibodies (HpIgG Ab), showing chronic infection, and Helicobacter pylori stool antigens (HpSA), showing active gastrointestinal colonization. Chi-square and Student t tests were used accordingly for statistical analysis. Helicobacter pylori seropositivity was 67.7% in the patients with hyperemesis gravidarum and 79.3% in the control group (χ2=1.02,P=.31). HpSA was detected in 22.6% of patients with hyperemesis gravidarum, whereas 6.9% of patients in the control group. The difference was not statistically significant (χ2=2.89,P=.08). In this study, no relation was found between Helicobacter pylori and hyperemesis gravidarum. The low social status of women in both groups could be one of the reasons for the high prevalence of Hp infection.

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Copyright © 2006 R. Sinan Karadeniz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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