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Infectious Diseases in Obstetrics and Gynecology
Volume 2007, Article ID 89059, 3 pages
http://dx.doi.org/10.1155/2007/89059
Case Report

Blastomyces Antigen Detection for Monitoring Progression of Blastomycosis in a Pregnant Adolescent

1Department of Obstetrics and Gynecology, University of Chicago, Chicago 60637, IL, USA
2Section of Infectious Diseases, Department of Pediatrics, University of Chicago, Chicago 60637, IL, USA
3Section of Infectious Diseases, Department of Pediatrics, University of Illinois, College of Medicine at Peoria, Peoria 61637, IL, USA
4MiraVista Diagnostics and MiraBella Technologies, Indianapolis 46241, IN, USA
5Section of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Chicago, Chicago 60637, IL, USA

Received 15 February 2007; Accepted 15 March 2007

Copyright © 2007 Megan Tarr et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Although disseminated blastomycosis is a rare complication in pregnancy, delay in diagnosis and treatment can be fatal. We investigate the use of the Blastomyces urine antigen in diagnosis following disease progression in the intrapartum, postpartum, and neonatal periods. We describe a case of disseminated blastomycosis in a pregnant adolescent and review the pertinent literature regarding treatment and monitoring blastomycosis in pregnancy and the neonatal periods. This is the first reported case in which the Blastomyces urine antigen is utilized as a method of following disease activity during pregnancy confirming absence of clinically evident disease in a neonate. Urine antigen detection for blastomycosis can be useful for following progression of disease in patients with disseminated blastomycosis in both the intrapartum and postpartum periods.