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Infectious Diseases in Obstetrics and Gynecology
Volume 2008, Article ID 628985, 5 pages
Case Report

Pulmonary Tuberculosis in a Young Pregnant Female: Challenges in Diagnosis and Management

Department of Medicine, University of Tennessee College of Medicine Chattanooga, Chattanooga, TN 37403, USA

Received 29 August 2007; Accepted 15 February 2008

Academic Editor: Sebastian Faro

Copyright © 2008 Manogna Maddineni and Mukta Panda. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. With the world becoming a global village, tuberculosis is no longer limited to endemic areas. Our case emphasizes the impact of immigration on infectious disease epidemiology and challenges associated with diagnosis and treatment in pregnancy. Case. A 21-year-old Hispanic female presented in preterm labor and was found to be hypoxic. Chest X-ray revealed a paratracheal mass which a CT scan confirmed. PPD test was positive. Bronchoalveolar lavage did not reveal acid-fast bacilli and biopsy revealed caseating granulomas. Diagnosis and treatment were challenging due to constraints in radiological investigations, lack of initial evidence of acid-fast bacilli, and toxic profile of medications. Due to her high risk, she was started on antituberculosis regimen. The diagnosis was confirmed on Day 26 when Mycobacterium tuberculosis was isolated by DNA probe. Conclusion. A high index of suspicion is required to recognize the changing face and disease spectrum of tuberculosis and initiate treatment for better outcomes.