Detection of Fastidious Vaginal Bacteria in Women with HIV Infection and Bacterial Vaginosis

Table 3

Sensitivity and specificity of detection of individual and combinations of bacteria for diagnosis of bacterial vaginosis compared to Amsel’s clinical criteria.

	Sensitivity	Specificity	OR (95% CI)	𝑃 value
Any Lactobacillus spp.	0%	100%	1.8 (0.15, 20.8)	.65
Any Lactobacillus crispatus	42%	63%	1.2 (0.39, 3.75)	.74
Any Gardnerella vaginalis	95%	32%	10.9 (1.3, 94)	.03
Any Leptotrichia/Sneathia	75%	68%	6.3 (1.8, 21)	.003
Any Megasphaera spp	50%	89%	8.3 (2.0, 35)	.004
Any BVAB1	29%	93%	5.4 (0.99, 29)	.051
Any BVAB2	63%	89%	13.9 (3.2, 60)	<.001
Any BVAB3	38%	89%	5.0 (1.2, 21)	.02
Any Megasphaera spp. OR BVAB2	71%	86%	14.6 (3.7, 58)	<.001
High Gardnerella vaginalis (>median)	75%	82%	13.8 (3.6, 53)	<.001