Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model
Figure 2
Intrauterine HK-GBS injection leads to TUNEL-positive apoptosis in the placenta. In the mouse placenta, there was TUNEL positive apoptosis after 14 hours of exposure to HK-GBS (d). The slides were treated with PBS for the negative control (a) and endonuclease for the positive control (b); animals were injected with media to assess baseline apoptosis levels (c). Data shown are the representative of 3 separate experiments.
