Clinical Study

Hepatitis B Response of Premature Infants after Primary and Booster Immunisation with a Diphtheria-Tetanus-Acellular Pertussis-Hepatitis B-Inactivated Poliovirus/Haemophilus Influenzae Type B Vaccine

Table 2

Anti-HBs seroprotection rates (SR) and geometric mean concentrations (GMC) by subgroup of preterm infants after primary course and booster dose (ATP cohort for immunogenicity).

SeroprotectionGMC
Gestational age (weeks)Nn%95% CImIU/ml95% CI

Primary course
34–36272592.675.7–99.1955.9461.1–1981.8
31–33242083.362.6–95.3418.0153.7–1136.4
28–30202010083.2–1001044.5633.9–1721
24–27202010083.2–100364.8184.5–721.5

Booster dose
34–36242291.773.0–99.02389.1919.4–6207.9
31–33231878.356.3–92.51127.2262.2–4845.2
28–30181810081.5–1003555.91881.1–6721.8
24–27181810081.5–1001054.0508.6–2184.2