Clinical Study

Hepatitis B Response of Premature Infants after Primary and Booster Immunisation with a Diphtheria-Tetanus-Acellular Pertussis-Hepatitis B-Inactivated Poliovirus/Haemophilus Influenzae Type B Vaccine

Table 5

Anti-HBs concentrations (mIU/ml) after all HBV doses in subjects who were non-responders to hepatitis B at the end of the primary and booster studies.

Post Extra HBVHBV
Gestational age (Weeks)Birth weight (kg)Percentile at birthWeight at 1st vaccination (kg)Percentile at 6 monthsWeight at 6 months (kg)Pre-primaryPost-primaryPre-boosterPost-boosterDose 1Dose 2Dose 3Persistence at 4 years (mIU/ml)

332.1754.4958.3 10 10 10 106903485NG176
352.0254256.7 10 10 10 10 10 1032128
320.6 101.7 54.4 10 10 10 10 10141NG64
310.8 101.7105.197 10 10 10 10NANG 10
332.0504.3>908.4 10 10 10 10 10 10 10 10
351.7103.6506.6 10 10 10 10 101087NGNA

NA = Not available; NG = Not given.