Research Article

The Emergence of Clostridium difficile Infection among Peripartum Women: A Case-Control Study of a C. difficile Outbreak on an Obstetrical Service

Table 1

Clinical characteristics and diagnostics of peripartum CDI cases.

AgeParityGestational age at CDI onset (wks)Significant underlying illnessObstetric complicationsGestational age at delivery (wks)Mode of deliveryAntibiotic typeToxin A (EIA)Toxin B gene (PCR)Toxin B (cytotoxin)Outcome (fever, diarrhea)Hospital days due to CDI

31031Marfan’s Synd.PTL36VDClindaNEGNDPOSF, DLong LOS
39127Twins, PPROM, chorio29VDAmp/Amox, Aug/Azy/EryPOSNDNDF, DLong LOS
525ppTwins, PTL, PPEM36CSClinda, Amp/Gent/Clinda, CephPOSNDPOSF, D, Total Colectomy8
191ppChorio41CSAmp/Gent/ClindaPOSNDPOSF, D1 (Re-ad)
311ppPPEM39CSAmp/Gent/
Clinda, Aug/Azy/Ery, Ceph
POSNDNDF, D0 (OP)
491ppMastitis42CSClinda, Ceph,
Aug/Azy/Ery, Other
POSNDNDF, D3 (Re-ad)
266ppPPROM, PPEM34VDAmp/Gent/Clinda, Aug/Azy/Ery, Amp/AmoxPOSPOSPOSF, D3 (Re-ad)
253PPChorio, PP hysterectomy37VDAmp/Gent/Clinda, CephPOSNDPOSF, D3 (Re-ad)
231PPChorio39CSAmp/Gent/ClindaNEGPOSNDF, D1 (Re-ad)
241ppNeck venous malformation37CSCephNEGPOSNDD0 (OP)
26122Class RF DM, CHTNFetal anomalies23VDNoneNEGPOSNDD5
413ppTwins, Pulm. Embolus, PPEM37CSAmp/Gent/Clinda, Aug/Azy/Ery, Ceph, OtherPOSNDNDF, DLong LOS
21126PPROM, chorio27CSAmp/Gent/Clinda, Aug/Azy/Ery, Ceph, OtherPOSNDNDF, D0 (Ante)
251ppChorio41CSAmp/Gent/ClindaPOSNDPOSF, D0 (OP)
293pp38CSCephPOSNDNDD0 (OP)
384ppChorio38CSAmp/Gent/Clinda, CephPOSPOSNEGF, D4 (Re-ad)
201ppOsteosarcomaPyelo, severe GHTN28VDOtherNEGPOSNDF, D5 (Re-ad)
32326Sickle Cell Dis.Pneumonia36CSAug/Azy/Ery, OtherNEGPOSNDF, DLong LOS
221ppPPEM41CSCeph, otherPOSNDNDF, D2 (Re-ad)
387ppPlacenta previa, abruption, pyelo30CSOtherPOSNDNDD0 (OP)

(Obstetric complications: PTL: preterm labor, PPROM: preterm, premature rupture of membranes, chorio: chorioamnionitis, PPEM: postpartum endometritis, pyelo: pyelonephritis, GHTN: gestational hypertension, mode of delivery: VD: vaginal delivery, CS: cesarean section; antibiotic type: clinda: clindamycin, Amp/Amox: ampicillin or amoxicillin, Aug/Azy/Ery: augmentin, azythromycin, or erythromycin, Amp/Gent/Clinda: ampicillin, gentamicin, and clindamycin, Ceph: cephalosporin; test results: ND: not done; hospital days: LOS: length of stay, Re-ad: patient readmitted, OP: outpatient therapy).