Review Article

Treatment of Acute Pelvic Inflammatory Disease

Table 3

Oral treatment recommendations for acute pelvic inflammatory diseasea.

Recommended regimens

(1) Ceftriaxone 250 mg IM in a single dose
  Plus
 Doxycycline 100 mg orally twice a day for 10–14 days
  With or without
 Metronidazole 500 mg orally twice a day for 10–14 days
(2) Cefoxitin 2 g IM in a single dose and Probenecid 1 g orally
administered concomitantly as a single dose
  Plus
 Doxycycline 100 mg orally twice a day for 10–14 days
  With or without
 Metronidazole 500 mg orally twice a day for 10–14 days
(3) Other parenteral third generation cephalosporins
  (e.g., ceftizoxime or cefotaxime) in a single dose
  Plus
 Doxycycline 100 mg orally twice a day for 10–14 days
  With or without
 Metronidazole 500 mg orally twice a day for 10–14 days

aCDC Sexually Transmitted Diseases Treatment Guidelines 2010 MMWR 2010 : 59 (no.-RR12).