aCases with matched controls available.|
bFour controls per case from the NSHDS (Northern Sweden Health and Disease Study) were matched with respect to age and date of plasma-sampling.
cA few subjects had cHSP60 IgG antibody results that were indeterminant and therefore excluded from the statistical analyses. Assigning them extreme values (all positive or all negative) did not change the main outcomes.
dA subgroup of type II malignancies where plasma samples were drawn 1.3 to 5.1 years prior to diagnosis.
The Pearson chi-square was used first,and when the expected frequency was <5, Fisher’s exact test was used.