Safety and Tolerability of Antiretrovirals during Pregnancy

Table 2

Laboratory adverse events.

Adverse event	𝑁 tested^#	𝑁 (%) with adverse event
		Grades 4*	Grades 3*	Grades 2*	Grades 1*
Anemia	110	2 (2%)	0	1 (1%)	4 (4%)
Thrombocytopenia	110	0	1 (1%)	0	2 (2%)
Neutropenia	110	0	0	3 (3%)	1 (1%)
Elevated ALT	98	1 (1%)	1 (1%)	4 (4%)	6 (6%)
Elevated AST	99	0	2 (2%)	4 (4%)	8 (8%)
Elevated bilirubin	98	2 (2%)	0	1 (1%)	2 (2%)
Elevated alkaline phosphatase	96	0	0	2 (2%)	17 (18%)
Elevated amylase	69	0	0	2 (3%)	1 (1%)

∗AE grades are the maximum observed grade for each pregnancy. Grading was performed according to the Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 1.0, dated December 2004 (http://rcc.tech-res.com/safetyandpharmacovigilance/).