Estimated annual impact in the USA of group child care on the rate of congenital CMV infection among multiparous Caucasians compared to multiparous non-Caucasians without group child care.
Caucasian
Non-Caucasian
No. live births/year
3,000,000*
1,000,000*
No. of seronegative mothers at conception
1,800,000 (60%)
200,000 (20%)&
No. with previous child at home
900,000 (50%)
Unknown
No. with previous child <3 years at conception
675,000 (75%)
Unknown
No. with child in day care
506,250 (75%)
Unknown
No. with shedding child
126,563 (25%)
Unknown
No. becoming infected during pregnancy
53,156 (42%)
15,600 (7.8%)&
No. of infants infected in utero (50%)
26,578
7,800
No. of infants with severe sequella+ (28%)
7,442
2,184
*US Bureau of Vital Statistics. +Death, I.Q. < 70, or deafness. &Based on data from [3, 13, 14].
