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Infectious Diseases in Obstetrics and Gynecology
Volume 2012, Article ID 287849, 4 pages
Review Article

Pregnancy in HIV-Positive Patients: Effects on Vaginal Flora

1Department of Obstetrics and Gynaecology, San Camillo-Forlanini Hospital, Piazza Carlo Forlanini 1, 00151 Rome, Italy
2Parasitology Unit, Bambino Gesù Children’s Hospital, IRCCS, Piazza Sant’Onofrio 4, 00165 Rome, Italy

Received 8 February 2012; Accepted 17 March 2012

Academic Editor: Francesco De Seta

Copyright © 2012 Cristina Vallone et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A high proportion of HIV-infected pregnant women present pathogenic organisms in their lower genital tract. This has been associated with the development of postpartum morbility, HIV transmission to the partner and offspring, and other gynaecological conditions, such as cervical dysplasia or cancer. Vaginal flora alterations can range from 47% in Western countries to 89% in Africa in pregnant HIV-positive patients, much higher than about 20% of the general population. Pathogen organism retrieval is high. As peripartum complications due to vaginal infections seem higher in HIV-positive patients, accurate investigation and treatment of such infections are strongly mandatory.