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Infectious Diseases in Obstetrics and Gynecology
Volume 2012 (2012), Article ID 587651, 7 pages
http://dx.doi.org/10.1155/2012/587651
Review Article

Evaluating Safer Conception Options for HIV-Serodiscordant Couples (HIV-Infected Female/HIV-Uninfected Male): A Closer Look at Vaginal Insemination

1Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94110, USA
2UCSF Bixby Center for Global Reproductive Health, San Francisco, CA 94105, USA
3Family AIDS Care and Education Services (FACES), Kenya

Received 21 February 2012; Accepted 6 July 2012

Academic Editor: Jean R. Anderson

Copyright © 2012 Okeoma Mmeje et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

HIV serodiscordant couples represent at least half of all HIV-affected couples worldwide. Many of these couples have childbearing desires. Safer methods of conception may allow for pregnancy while minimizing the risk of sexual transmission of HIV. In serodiscordant partnerships with an HIV-infected female and HIV-uninfected male, vaginal insemination of a partner's semen during the fertile period coupled with 100% condom use may be the safest method of conception.