Research Article

Incidence of Pregnancy after Initiation of Antiretroviral Therapy in South Africa: A Retrospective Clinical Cohort Analysis

Table 1

Characteristics of 5,996 women initiating HAART in Johannesburg, South Africa from 1 April 2004 to 30 September 2009 by pregnancy status at baseline.

Baseline characteristicsPregnant ( = 586)Not pregnant ( = 5,410) -value

Age (years)30 (26, 33)34 (29, 38)<0.0001
Weight (kg)68 (60, 77)57 (49, 65)<0.0001
Body mass index (kg/m2)26.5 (23.3, 29.7)22.2 (19.5, 25.5)<0.0001
WHO stage III or IV100 (18.2)2372 (43.1)<0.0001
Hemoglobin, low123 (30.9)2918 (54.7)<0.0001
CD4 count (cells/mm3)156 (106, 200)93 (35, 164)<0.0001
CD4 count ≤ 50 (cells/mm3)45 (8.8)1739 (32.6)<0.0001

Categorical variables are expressed as number (% total); continuous variables are expressed as median (interquartile range). -values are two-sided by chi-square test or Wilcoxon rank sum test. adjustment for altitude, lower limit of normal hemoglobin is 11.35 and 10.35 g/dL for nonpregnant and pregnant women, respectively.