Medical and Infectious Complications Associated with Pyelonephritis among Pregnant Women at Delivery

Table 2

Preexisting medical conditions present at time of delivery in hospital discharges among women with pyelonephritis compared to women without pyelonephritis, Nationwide Inpatient Sample years 2008–2010 (12,628,746 deliveries).

Condition, 𝑛 (%)	Pyelo; 𝑛 = 26,397	No Pyelo; 𝑛 = 12,602,349	OR (95% CI)	𝑃 value
Heart disease
Cardiomyopathy	39 (0.1)	5705 (0.04)	3.3 (2.4, 4.4)	<0.0001
Valvular heart disease	108 (0.4)	55,209 (0.4)	0.9 (0.8, 1.1)	0.513
Pulmonary disease
Asthma	1423 (5.4)	410,193 (3.3)	1.7 (1.6, 1.8)	<0.0001
Endocrine disorders
Diabetes (nongestational)	560 (2.1)	133,796 (1.1)	2.0 (1.9, 2.2)	<0.0001
Thyroid disorder	510 (1.9)	299,418 (2.4)	0.8 (0.7, 0.9)	<0.0001
Autoimmune disorders
Systemic lupus erythem.	77 (0.3)	16,596 (0.1)	2.2 (1.7, 2.7)	<0.0001
Hematologic disorders
Thrombophilia/APS	141 (0.5)	71,313 (0.6)	0.9 (0.8, 1.1)	0.516
Anemia	5406 (20.5)	1,358,360 (10.8)	2.1 (2.1, 2.2)	<0.0001
Thrombocytopenia	443 (1.7)	114,254 (0.9)	1.9 (1.7, 2.0)	<0.0001
Sickle cell/thalassemia	86 (0.3)	19,559 (0.1)	2.1 (1.7, 2.6)	<0.0001
Drugs/alcohol/tobacco
Drug use	852 (3.2)	164,788 (1.3)	2.5 (2.3, 2.7)	<0.0001
Alcohol use	56 (0.2)	14,034 (0.1)	1.9 (1.5, 2.5)	<0.0001
Tobacco	2531 (9.6)	792,389 (6.3)	1.6 (1.5, 1.6)	<0.0001
Chronic hypertension/renal failure
Chronic hypertension	488 (1.8)	248,440 (2.0)	0.9 (0.8, 1.02)	0.148
Chronic renal failure	40 (0.1)	5012 (0.04)	3.8 (2.8, 5.1)	<0.0001

APS: antiphospholipid antibody syndrome.