Benzoyl Peroxide Formulated Polycarbophil/Carbopol 934P Hydrogel with Selective Antimicrobial Activity, Potentially Beneficial for Treatment and Prevention of Bacterial Vaginosis

Table 1

Zones of inhibition (mm) from well diffusion assay^a.

BP% (w/w)	G. vaginalis	L. vaginalis	L. gasseri	L. plantarum	L. acidophilus
0 (base gel)	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
0.01	0.50±0.00	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
0.10	0.67±0.26	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
0.25	1.08±0.20	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
0.50	1.17±0.26	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
1.00	1.67±0.26	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
2.50	1.92±0.38	0.50±0.00	0.50±0.00	0.50±0.00	0.50±0.00
5.00	2.25±0.42	0.50±0.00	0.50±0.00	0.50±0.00	0.50±0.26
7.50	2.42±0.38	0.50±0.00	0.50±0.00	0.50±0.00	0.58±0.20
10.00	2.58±0.38	0.50±0.00	0.75±0.27	0.50±0.00	0.67±0.26
Clindamycin (100 𝜇g/mL)	22.20±0.80	17.30±0.50	19.00±0.60	21.80±0.80	26.00±0.90

aThe distance is measured from the edge of the loading well to the edge of the inhibition zone in millimeters using Vernier calipers. Experiments were conducted at least two times in triplicates. Mean values and their standard deviations are provided.