TY - JOUR A2 - Wald, Anna AU - Imanishi, Maho AU - Routh, Janell A. AU - Klaber, Marigny AU - Gu, Weidong AU - Vanselow, Michelle S. AU - Jackson, Kelly A. AU - Sullivan-Chang, Loretta AU - Heinrichs, Gretchen AU - Jain, Neena AU - Albanese, Bernadette AU - Callaghan, William M. AU - Mahon, Barbara E. AU - Silk, Benjamin J. PY - 2015 DA - 2015/02/15 TI - Estimating the Attack Rate of Pregnancy-Associated Listeriosis during a Large Outbreak SP - 201479 VL - 2015 AB - Background. In 2011, a multistate outbreak of listeriosis linked to contaminated cantaloupes raised concerns that many pregnant women might have been exposed to Listeria monocytogenes. Listeriosis during pregnancy can cause fetal death, premature delivery, and neonatal sepsis and meningitis. Little information is available to guide healthcare providers who care for asymptomatic pregnant women with suspected L. monocytogenes exposure. Methods. We tracked pregnancy-associated listeriosis cases using reportable diseases surveillance and enhanced surveillance for fetal death using vital records and inpatient fetal deaths data in Colorado. We surveyed 1,060 pregnant women about symptoms and exposures. We developed three methods to estimate how many pregnant women in Colorado ate the implicated cantaloupes, and we calculated attack rates. Results. One laboratory-confirmed case of listeriosis was associated with pregnancy. The fetal death rate did not increase significantly compared to preoutbreak periods. Approximately 6,500–12,000 pregnant women in Colorado might have eaten the contaminated cantaloupes, an attack rate of ~1 per 10,000 exposed pregnant women. Conclusions. Despite many exposures, the risk of pregnancy-associated listeriosis was low. Our methods for estimating attack rates may help during future outbreaks and product recalls. Our findings offer relevant considerations for management of asymptomatic pregnant women with possible L. monocytogenes exposure. SN - 1064-7449 UR - https://doi.org/10.1155/2015/201479 DO - 10.1155/2015/201479 JF - Infectious Diseases in Obstetrics and Gynecology PB - Hindawi Publishing Corporation KW - ER -