Review Article

Mycoplasma genitalium: An Overlooked Sexually Transmitted Pathogen in Women?

Table 1

Summary of M. genitalium prevalence according to various studies in women.

SourceStudy designStudy populationOverall M. genitalium prevalence (%)

Gaydos et al. [2]Cross-sectional study324 women attending STI clinics in Baltimore. Detected by transcription mediated amplification from vaginal, endocervical, and urine swabs19.2

Oakeshott et al. [8]Prospective study2378 sexually active female students (mean age of 21) followed up between 2004 and 2008 in London. Tested vaginal swabs by PCR3.3

Haggerty et al. [15]Multicenter randomized controlled prospective study, PEACH studyStored cervical and endometrial specimens of 682 women treated with cefoxitin and doxycycline for clinically suspected PID tested by PCR15

Clarivet et al. [25]Cross-sectional study743 asymptomatic women attending free and anonymous STI clinics from April to August 2009. Detected by PCR in first void urine (FVU) sample0.1

Falk et al. [23]Cross-sectional study465 female STI clinic attendees (mean age of 24) in Orebro, Sweden. Tested FVU and endocervical samples by PCR6

Hancock et al. [26]Cross-sectional study1090 women attending the Public Health-Seattle & Kig County STI Clinic in Seattle, WA. M. genitalium detected by TMA from self-obtained vaginal swabs 7.7

Bjartling et al. [27]Cross-sectional case-control study679 women attending a gynecological outpatient clinic from 2003 through 2008. Tested urine and vaginal swabs by PCR2.1

Uno et al. [28]Cross-sectional study200 women visiting the Obstetrics and Gynecology Department in Kizawa Memorial Hospital and Jaysaki Women’s Clinic in Japan. Tested cervical swabs using PCR.6.8

Gomih-Alakija et al. [29]Cross-sectional study350 female sex workers aged 18–50 years in Nairobi, Kenya. Tested cervical samples by TMA12.9

Bradshaw et al. [30]Prospective study313 women attending Melbourne Sexual Health Center, Australia, between March 2005 and November 2007 with cervicitis/pelvic inflammatory disease and sexual contacts of proven M. genitalium, infected partners. Cervical, vaginal swabs, or FVU samples analyzed by PCR10

Andersen et al. [31]Cross-sectional study921 women aged 21–23 provided self-collected vaginal samples by PCR2.3