Research Article
Time-Kill Kinetics of Rezafungin (CD101) in Vagina-Simulative Medium for Fluconazole-Susceptible and Fluconazole-Resistant Candida albicans and Non-albicans Candida Species
Table 1
MIC values for time-kill assay Candida strains in VSM (pH 4.2) or RPMI (pH 7.0).
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values were determined three times, independently. At most there was a 2-fold range in variation for each drug/strain combination MIC value between replicates and modal values are listed. 2Susceptibility to FLU as defined per CLSI 24 h broth microdilution interpretive criteria [21]. 3ATCC describes strain 200918 as FLU-R strain although the CLSI MIC value of 32 μg/ml derived in this study is technically characterized as “susceptible-dose dependent” per CLSI interpretive criteria [21]. |