Infectious Diseases in Obstetrics and Gynecology / 2018 / Article / Tab 3

Research Article

The Role of Polymorphonuclear Leukocyte Counts from Urethra, Cervix, and Vaginal Wet Mount in Diagnosis of Nongonococcal Lower Genital Tract Infection

Table 3

Clinical and microscopic criteria for LGTI in the subgroup for Chlamydia trachomatis.

Single tests and test combinationNSensitivity95% CISpecificity95% CIPPV95% CINPV95% CINNDTrue pos.

Urethra: PMNL≥51350,770,59 – 0,900,580,51 – 0,640,180,12 – 0,250,960,91 – 0,98324
Urethra: PMNL≥10500,420,25 – 0,610,860,81 – 0,900,260,15 – 0,400,930,89 – 0,96413
Wet smear: WBC>Epith550,350,19 – 0,550,830,78 – 0,880,200,10 – 0,330,920,87 – 0,95511
Cervix: PMNL>30910,520,33 – 0,700,710,65 – 0,770,180,10 – 0,270,930,88 – 0,96416
Clinical cervicitis710,420,25 – 0,610,780,72 – 0,830,180,10 – 0,290,920,87 – 0,95513
Urethra: PMNL≥5Cervix: PMNL>30570,480,30 – 0,670,840,79 – 0,880,260,16 – 0,400,930,89 – 0,96315
Urethra: PMNL≥5Wet smear: WBC>Epith340,290,14 – 0,480,900,86 – 0,940,260,13 – 0,440,920,87 – 0,9559
Urethra: PMNL≥5Clinical cervicitis410,320,17 – 0,510,880,84 – 0,920,240,12 – 0,400,920,88 – 0,95510
Urethra: PMNL≥10Cervix: PMNL>30300,350,19 – 0,550,930,89 – 0,960,370,20 – 0,560,920,88 – 0,95411
Urethra: PMNL≥10Wet smear: WBC>Epith170,160,05 – 0,340,950,92 – 0,980,290,10 – 0,560,910,87 – 0,9495
Urethra: PMNL≥10Clinical cervicitis150,160,05 – 0,340,960,93 – 0,980,330,12 – 0,620,910,87 – 0,9485
Cervix: PMNL>30Clinical cervicitis340,260,12 – 0,450,900,86 – 0,930,240,11 – 0,410,910,87 – 0,9468
Wet smear: WBC>EpithClinical cervicitis300,230,10 – 0,410,910,87 – 0,940,230,10 – 0,420,910,87 – 0,9477
Wet smear: WBC>EpithCervix: PMNL>30250,260,12 – 0,450,940,90 – 0,960,320,15 – 0,540,910,87 – 0,9458
Urethra: PMNL≥5Cervix: PMNL>30Wet smear: WBC>Epith200,230,10 – 0,410,950,92 – 0,970,350,15 – 0,590,910,87 – 0,9457
Urethra: PMNL≥5Cervix: PMNL>30Clinical cervicitis250,230,10 - 0,410,930,89 – 0,960,280,12 – 0,490,910,87 – 0,9467
Urethra: PMNL≥5Wet smear: WBC>EpithClinical cervicitis210,190,07 – 0,370,940,91 – 0,970,290,11 – 0,520,910,87 – 0,9476
Urethra: PMNL≥10Cervix: PMNL>30Wet smear: WBC>Epith120,160,05 – 0,340,970,95 – 0,990,420,15 – 0,720,910,87 – 0,9475
Urethra: PMNL≥10Cervix: PMNL>30Clinical cervicitis110,160,05 – 0,340,980,95 – 0,990,450,17 – 0,770,910,87 – 0,9475
Urethra: PMNL≥10Wet smear: WBC>EpithClinical cervicitis90,100,02 – 0,260,980,95 – 0,990,330,07 – 0,700,900,86 – 0,93143
Cervix: PMNL>30Wet smear: WBC>EpithClinical cervicitis180,190,07 – 0,370,950,92 – 0,980,330,13 – 0,590,910,87 – 0,9466
Urethra: PMNL≥5Cervix: PMNL>30Wet smear: WBC>EpithClinical cervicitis150,160,05 – 0,340,960,93 – 0,980,330,12 – 0,620,910,87 – 0,9485
Urethra: PMNL≥10Cervix: PMNL>30Wet smear: WBC>EpithClinical cervicitis70,100,02 – 0,260,980,96 – 1,000,430,10 – 0,820,900,86 – 0,93123

PMNL: polymorphonuclear leucocytes per field in 1000x stained smear.
PPV: positive predictive value. NPV: negative predictive value. NND: number of patients that must be tested in order to produce one correctly classified positive test.
WBC>Epith: more white blood cells than epithelial cells in vaginal wet smear.

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