New Sensitive Kinetic Spectrophotometric Methods for Determination of Omeprazole in Dosage Forms

Table 7

Determination of OMZ in its dosage forms by the proposed methods.

Dosage form	Label claim (% ± SD)^a
	Initial rate method		Fixed-time method		Reference^c method
	Iodine	DDQ	Iodine	DDQ
Gastrazole capsules	99.82 ±1.65	98.91 ±1.78	100.24 ±1.84	99.20 ±1.53	100.40 ±1.34
𝑡-value^b	0.63	1.51	0.2	1.32
𝐹-value^b	1.52	1.76	1.89	1.30
Losec tablets	99.41 ±1.24	99.70 ±1.13	100.32 ±0.94	99.93 ±1.13	100.90 ±1.18
𝑡-value^b	1.96	1.64	0.14	0.64
𝐹-value^b	1.10	1.09	0.63	0.92

a Values are mean of five determinations.
b The tabulated values of 𝑡 and 𝐹 at 95% confidence limit are 2.78 and 6.39, respectively.
c Reference [12].