Stability Indicating HPLC Determination of Risperidone in Bulk Drug and Pharmaceutical Formulations

Table 4

Summary of forced degradation results.

Sr. no.	Stress/exposure condition	Drug remained/20 𝜇g/mL ± SD (𝑛=3)	Retention time of degradants	% Recovery	% Degradation
(1)	Acid degradation	14.62±0.16	4.20	73.10	26.89
(2)	Base degradation	16.49±0.16	2.62	82.46	17.53
(3)	Oxidation	6.29±0.08	2.67	31.45	68.54
(4)	Thermal degradation	13.98±0.11	2.75	69.90	30.09
(5)	Photo degradation	14.67±0.12	2.76	73.37	26.62