Research Article
Utility of N-Bromosuccinimide for the Titrimetric and Spectrophotometric Determination of Famotidine in Pharmaceutical Formulations
Table 3
Evaluation of intraday and interday accuracy and precision.
| Method | FMT taken | Intraday accuracy and precision | Interday accuracy and precision | FMT found | %RE | %RSD | FMT found | %RE | %RSD |
| Titrimetry method A | 3.0 | 3.08 | 2.66 | 1.06 | 3.10 | 3.3 | 1.32 | 6.0 | 6.1 | 1.67 | 1.01 | 6.13 | 2.17 | 0.97 | 9.0 | 8.75 | 2.77 | 0.95 | 8.72 | 3.11 | 1.18 | Method B | 1.0 | 1.02 | 2.01 | 1.02 | 0.97 | 3.01 | 1.12 | 5.0 | 4.94 | 1.22 | 0.98 | 4.89 | 2.22 | 1.34 | 7.0 | 6.92 | 1.14 | 1.11 | 6.87 | 1.86 | 1.29 | Spectrophotometry method C | 3.0 | 3.07 | 2.33 | 0.92 | 3.10 | 3.33 | 1.15 | 4.5 | 4.59 | 2.00 | 1.14 | 4.61 | 2.44 | 1.28 | 6.0 | 5.8 | 3.33 | 1.02 | 5.82 | 3.01 | 1.11 | Method D | 0.6 | 0.62 | 3.33 | 1.25 | 0.58 | 3.33 | 1.35 | 1.8 | 1.85 | 2.78 | 1.21 | 1.76 | 2.22 | 1.29 | 3.0 | 2.94 | 2.02 | 1.13 | 3.10 | 3.33 | 1.17 |
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RE: Relative error and RSD: Relative standard deviation. In titrimetry, FMTs taken/found are in mg and they are g mL−1 in spectrophotometry.
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