Research Article

Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms

Table 2

Determination of alendronate sodium in the presence of possible excipients (5 μg mL−1 of alendronate sodium was taken for interferences studies).

ExcipientAmount taken
(g mL−1)
% Recovery ± RSD ( )
method A
%  Recovery RSD ( )
method B

Microcrystalline cellulose30099.6 + 0.2599.6 + 0.25
Anhydrous lactose30099.5 + 0.2599.5 + 0.25
Magnesium stearate200100.1 + 0.30100.1 + 0.30
Croscarmellose sodium10099.8 + 0.4099.8 + 0.40
Calcium phosphate5099.4 + 0.4599.4 + 0.45