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International Journal of Analytical Chemistry
Volume 2012 (2012), Article ID 282574, 40 pages
http://dx.doi.org/10.1155/2012/282574
Review Article

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India

Received 9 August 2011; Revised 23 October 2011; Accepted 9 November 2011

Academic Editor: Troy D. Wood

Copyright © 2012 Shibdas Banerjee and Shyamalava Mazumdar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [81 citations]

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  • Shruti Chopra, Murali Pendela, Jos Hoogmartens, Ann Van Schepdael, and Erwin Adams, “Impurity profiling of capreomycin using dual liquid chromatography coupled to mass spectrometry,” Talanta, vol. 100, pp. 113–122, 2012. View at Publisher · View at Google Scholar
  • Sandeep Goyal, Shibdas Banerjee, and Shyamalava Mazumdar, “ Oxygenation of Monoenoic Fatty Acids by CYP175A1, an Orphan Cytochrome P450 from Thermus thermophilus HB27 ,” Biochemistry, vol. 51, no. 40, pp. 7880–7890, 2012. View at Publisher · View at Google Scholar
  • Elizabeth M. Yuill, Niya Sa, Steven J. Ray, Gary M. Hieftje, and Lane A. Baker, “Electrospray Ionization from Nanopipette Emitters with Tip Diameters of Less than 100 nm,” Analytical Chemistry, vol. 85, no. 18, pp. 8498–8502, 2013. View at Publisher · View at Google Scholar
  • Valerie Gabelica, Helmut Grubmueller, and Modesto Orozco, “Proteins in the gas phase,” Wiley Interdisciplinary Reviews-Computational Molecular Science, vol. 3, no. 4, pp. 408–425, 2013. View at Publisher · View at Google Scholar
  • Hanna Skubatz, and William N. Howald, “Two Global Conformation States of a Novel NAD(P) Reductase Like Protein of the Thermogenic Appendix of the Sauromatum guttatum Inflorescence,” The Protein Journal, 2013. View at Publisher · View at Google Scholar
  • Shibdas Banerjee, “Induction of protein conformational change inside the charged electrospray droplet,” Journal Of Mass Spectrometry, vol. 48, no. 2, pp. 193–204, 2013. View at Publisher · View at Google Scholar
  • Yi-Tzu Cho, Min-Zong Huang, Sih-You Wu, Ming-Feng Hou, Jianjun Li, and Jentaie Shiea, “Using electrospray laser desorption ionization mass spectrometry to rapidly examine the integrity of proteins stored in various solutions,” Analytical and Bioanalytical Chemistry, 2013. View at Publisher · View at Google Scholar
  • Jose C. J. M. D. S. Menezes, Jose A. S. Cavaleiro, and M. Rosario M. Domingues, “Structural analysis of 2-arylidene-1-indanone derivatives by electrospray ionization tandem mass spectrometry,” Rapid Communications in Mass Spectrometry, vol. 27, no. 21, pp. 2461–2471, 2013. View at Publisher · View at Google Scholar
  • Aurelie Periat, Serge Rudaz, Julien Boccard, Jean-Luc Veuthey, and Davy Guillarme, “Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry,” Journal Of Chromatography A, vol. 1312, pp. 49–57, 2013. View at Publisher · View at Google Scholar
  • Mathivathani Kandiah, and Pawel L. Urban, “Advances in ultrasensitive mass spectrometry of organic molecules,” Chemical Society Reviews, vol. 42, no. 12, pp. 5299–5322, 2013. View at Publisher · View at Google Scholar
  • S. S. Zalesskiy, V. V. Kachala, L. L. Khemchyan, A. A. Grachev, V. P. Ananikov, A. S. Kashin, and N. V. Orlov, “Target-oriented analysis of gaseous, liquid and solid chemical systems by mass spectrometry, nuclear magnetic resonance spectroscopy and electron microscopy,” Russian Chemical Reviews, vol. 82, no. 7, pp. 648–685, 2013. View at Publisher · View at Google Scholar
  • Saurabh K. Srivastava, Vincent J. B. Ruigrok, Albert J. R. Heck, Natalie J. Thompson, Anke K. Trilling, Maarten A. Jongsma, Cees van Rijn, and Jules Beekwilder, “16 kDa Heat Shock Protein from Heat-Inactivated Mycobacterium tuberculosis Is a Homodimer - Suitability for Diagnostic Applications with Specific Llama VHH Monoclonals,” Plos One, vol. 8, no. 5, 2013. View at Publisher · View at Google Scholar
  • Jinyu Li, Giulia Rossetti, Jens Dreyer, Simone Raugei, Emiliano Ippoliti, Bernhard Luescher, and Paolo Carloni, “Molecular Simulation-Based Structural Prediction of Protein Complexes in Mass Spectrometry: The Human Insulin Dimer,” Plos Computational Biology, vol. 10, no. 9, 2014. View at Publisher · View at Google Scholar
  • Cristina Lento, Gerald F. Audette, and Derek J. Wilson, “Time-resolved electrospray mass spectrometry — a brief history,” Canadian Journal of Chemistry, pp. 1–6, 2014. View at Publisher · View at Google Scholar
  • R. You, M. Li, S. Guha, G. W. Mulholland, and M. R. Zachariah, “Bionanoparticles as Candidate Reference Materials for Mobility Analysis of Nanoparticles,” Analytical Chemistry, pp. 140707072047007, 2014. View at Publisher · View at Google Scholar
  • Oliver Frank, Johanna Karoline Kreissl, Andreas Daschner, and Thomas Hofmann, “ Accurate Determination of Reference Materials and Natural Isolates by Means of Quantitative 1 H NMR Spectroscopy ,” Journal of Agricultural and Food Chemistry, pp. 140311124457004, 2014. View at Publisher · View at Google Scholar
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  • Ze-Qin Guo, Dong-Mei Fang, Jian-Hua Wang, Guo-Lin Zhang, and Zhi-Jun Wu, “[M–H]+ ions in 3-alkyl substituted indoles detected by electrospray mass spectrometry,” International Journal of Mass Spectrometry, 2014. View at Publisher · View at Google Scholar
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  • Szymon Filip, Jerome Zoidakis, Antonia Vlahou, and Harald Mischak, “Advances in urinary proteome analysis and applications in systems biology,” Bioanalysis, vol. 6, no. 19, pp. 2549–2569, 2014. View at Publisher · View at Google Scholar
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  • Karina Tveen-Jensen, Frank Gesellchen, Rab Wilson, Corinne M. Spickett, Jonathan M. Cooper, and Andrew R. Pitt, “Interfacing low-energy SAW nebulization with Liquid Chromatography-Mass Spectrometry for the analysis of biological samples,” Scientific Reports, vol. 5, 2015. View at Publisher · View at Google Scholar
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  • Corinne M. Spickett, and Andrew R. Pitt, “Oxidative Lipidomics Coming of Age: Advances in Analysis of Oxidized Phospholipids in Physiology and Pathology,” Antioxidants & Redox Signaling, pp. 150326134633009, 2015. View at Publisher · View at Google Scholar
  • Jae Kyoo Lee, Samuel Kim, Hong Gil Nam, and Richard N. Zare, “Microdroplet fusion mass spectrometry for fast reaction kinetics,” Proceedings of the National Academy of Sciences, vol. 112, no. 13, pp. 3898–3903, 2015. View at Publisher · View at Google Scholar
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  • Jens Kruse, Marion Abraham, Wulf Amelung, Christel Baum, Roland Bol, Oliver Kühn, Hans Lewandowski, Jörg Niederberger, Yvonne Oelmann, Christopher Rüger, Jakob Santner, Meike Siebers, Nina Siebers, Marie Spohn, Johan Vestergren, Angela Vogts, and Peter Leinweber, “Innovative methods in soil phosphorus research: A review,” Journal of Plant Nutrition and Soil Science, 2015. View at Publisher · View at Google Scholar
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