Titrimetric and Spectrophotometric Methods for the Assay of Ketotifen Using Cerium(IV) and Two Reagents
Table 2
Sensitivity and regression parameters.
Parameter
Method B
Method C
, nm
460
470
Colour stability, min
60
15
Linear range, g mL−1
0.4–8.0
0.4–10
Molar absorptivity (), L mol−1 cm−1
4.0 × 104
3.7 × 104
Sandell sensitivity*, g cm−2
0.0105
0.0136
Limit of detection (LOD), g mL−1
0.39
0.43
Limit of quantification (LOQ), g mL−1
1.19
1.32
Regression equation,
Intercept ()
0.8744
0.8082
Slope ()
−0.0914
−0.0815
Standard deviation of ()
2.2 × 10−2
6.6 × 10−2
Standard deviation of ()
4.9 × 10−3
7.3 × 10−3
Regression coefficient ()
−0.9998
−0.9990
Limit of determination as the weight in g per mL of solution, which corresponds to an absorbance of measured in a cuvette of cross-sectional area 1 cm2 and = 1 cm. , where is the absorbance, is concentration in g mL−1, is intercept, and is slope.
