Utilization of N-Bromosuccinimide as a Brominating Agent for the Determination of Sumatriptan Succinate in Bulk Drug and Tablets

Table 6

Results of recovery study by standard addition method.

Tablets studied	Method A				Method B				Method C
	STS in; tablets; mg mL^−1	Pure STS; added; mg mL^−1	Total found; mg mL^−1	Pure STS recovered*; Percent ± SD	STS in; tablets; µg mL^−1	Pure STS; added µg mL^−1	Total found; µg mL^−1	Pure STS recovered*; Percent ± SD	STS in; tablets; µg mL^−1	Pure STS; added µg mL^−1	Total found; µg mL^−1	Pure STS recovered*; Percent ± SD
Suminat-25	2.98	1.5	4.47	99.33±0.07	4.57	2.25	6.87	102.2±1.15	1.02	0.5	1.51	98.20±0.91
	2.98	3.0	6.02	101.3±0.05	4.57	4.50	9.15	101.8±0.93	1.02	1.0	2.04	101.9±1.30
	2.98	4.5	7.60	102.7±0.05	4.57	6.75	11.4	101.2±0.82	1.02	1.5	2.54	101.3±0.89
Suminat-50	3.03	1.5	4.56	102.0±0.05	4.55	2.25	6.78	99.11±1.16	0.99	0.5	1.50	102.4±1.56
	3.03	3.0	6.00	99.00±0.06	4.55	4.50	9.15	102.2±0.68	0.99	1.0	2.00	101.7±0.96
	3.03	4.5	7.60	101.6±0.05	4.55	6.75	11.5	103.0±1.21	0.99	1.5	2.52	102.0±1.03

∗Mean value of three determinations.