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International Journal of Analytical Chemistry
Volume 2015, Article ID 678579, 8 pages
http://dx.doi.org/10.1155/2015/678579
Research Article

Determination of Glucocorticoids in UPLC-MS in Environmental Samples from an Occupational Setting

1Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy
2Environmental Research Center, Salvatore Maugeri Foundation, Via S. Maugeri 10, 27100 Pavia, Italy
3Hospital Operating Unit of Occupational Medicine (UOOML), Salvatore Maugeri Foundation, Via S. Maugeri 10, 27100 Pavia, Italy

Received 29 September 2014; Revised 13 February 2015; Accepted 19 February 2015

Academic Editor: Troy D. Wood

Copyright © 2015 Enrico Oddone et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Farina, P. de Micheli, P. Basso, P. P. Castelli, G. Locati, and G. C. Secchi, “Technopathy from steroids in the drug industry: first report of a syndrome from exogenous hypercortisolism in workers engaged in the production of steroids,” Medicina del Lavoro, vol. 68, no. 3, pp. 167–177, 1977. View at Google Scholar · View at Scopus
  2. R. W. Newton, M. C. K. Browning, J. Iqbal, N. Piercy, and D. G. Adamson, “Adrenocortical suppression in workers manufacturing synthetic glucocorticoids,” British Medical Journal, vol. 1, no. 6105, pp. 73–74, 1978. View at Publisher · View at Google Scholar · View at Scopus
  3. R. W. Newton, M. C. K. Browning, P. C. Nicholson, and D. A. E. Mowat, “Adrenocortical suppression in workers employed in manufacturing synthetic glucocorticosteroids: solutions to a problem,” British Journal of Industrial Medicine, vol. 39, no. 2, pp. 179–182, 1982. View at Google Scholar · View at Scopus
  4. L. N. Vandenberg, T. Colborn, T. B. Hayes et al., “Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses,” Endocrine Reviews, vol. 33, no. 3, pp. 378–455, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. R. A. Fenske, C. Schulter, C. Lu, and E. H. Allen, “Incomplete removal of the pesticide captan from skin by standard handwash exposure assessment procedures,” Bulletin of Environmental Contamination and Toxicology, vol. 61, no. 2, pp. 194–201, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. D. H. Brouwer, M. F. Boeniger, and J. van Hemmen, “Hand wash and manual skin wipes,” The Annals of Occupational Hygiene, vol. 44, no. 7, pp. 501–510, 2000. View at Publisher · View at Google Scholar · View at Scopus
  7. H. Marquart, D. H. Brouwer, and J. J. van Hemmen, “Removing pesticides from the hands with a simple washing procedure using soap and water,” Journal of Occupational and Environmental Medicine, vol. 44, no. 11, pp. 1075–1082, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. C. Aprea, C. Sciarra, L. Lunghini, and N. Bozzi, “Pesticides,” in Environmental and Biological Monitoring of Occupational Exposures to Xenobiotics, L. Minoia, Ed., 2000. View at Google Scholar
  9. A. Polettini, G. M. Bouland, and M. Montagna, “Development of a coupled-column liquid chromatographic-tandem mass spectrometric method for the direct determination of betamethasone in urine,” Journal of Chromatography B: Biomedical Applications, vol. 713, no. 2, pp. 339–352, 1998. View at Publisher · View at Google Scholar · View at Scopus
  10. V. Cirimele, P. Kintz, V. Dumestre, J. P. Goullé, and B. Ludes, “Identification of ten corticosteroids in human hair by liquid chromatography-ionspray mass spectrometry,” Forensic Science International, vol. 107, no. 1–3, pp. 381–388, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Hedmer, B. A. G. Jönsson, and O. Nygren, “Development and validation of methods for environmental monitoring of cyclophosphamide in workplaces,” Journal of Environmental Monitoring, vol. 6, no. 12, pp. 979–984, 2004. View at Publisher · View at Google Scholar · View at Scopus
  12. C. Sottani, R. Turci, R. Schierl et al., “Simultaneous determination of gemcitabine, taxol, cyclophosphamide and ifosfamide in wipe samples by high-performance liquid chromatography/tandem mass spectrometry: protocol of validation and uncertainty of measurement,” Rapid Communications in Mass Spectrometry, vol. 21, no. 7, pp. 1289–1296, 2007. View at Publisher · View at Google Scholar · View at Scopus