A New Sensitive Sensor for Simultaneous Differential Pulse Voltammetric Determination of Codeine and Acetaminophen Using a Hydroquinone Derivative and Multiwall Carbon Nanotubes Carbon Paste Electrode

Table 4

Determination of codeine in pharmaceutical samples using HTP-MWCNT-CPE.

Sample	Added (mg)		Found^a (mg)		RSD (%)		Recovery (%)		Labelled value		Statistical -test^b		Company/batch number
	COD	AC	COD	AC	COD	AC	COD	AC	COD	AC	COD	AC
AC tablet	—	—	—	324.2 ± 3.3	—	1.0	—	99.7	—	325.0	—	0.5	Jalinous/92046
	10.0	—	9.9 ± 0.1	324.2 ± 3.3	1.0	1.0	99.1	—	—	—	—	—
	15.0	10.0	15.1 ± 0.2	335.2 ± 3.4	1.0	1.0	100.7	100.0	—	—	—	—
AC tablet	—	—	—	504.1 ± 5.0	—	—	—	100.8	—	500.0	—	1.6	Soha/91025
	10.0	—	10.1 ± 0.1	503.0 ± 5.0	1.1	1.0	101.2	—	—	—	—	—
	15.0	25.0	14.9 ± 0.2	526.1 ± 5.2	1.0	1.0	99.2	100.2	—	—	—	—
AC-COD tablet	—	—	—	—	—	—	—	—	10	300.0	—	—	Pharmachemie/071
	—	—	10.1 ± 0.1	298.9 ± 3.1	1.1	1.0	100.8	99.6	—	—	1.4	0.7
	5.0	—	14.9 ± 0.2	298.1 ± 3.2	1.0	1.1	99.4	—	—	—	—	—
	—	5.0	9.8 ± 0.1	306.0 ± 3.3	1.2	1.0	98.2	100.3	—	—	—	—
	5.0	5.0	15.4 ± 0.2	304.1 ± 3.2	1.0	1.0	102.4	99.7	—	—	—	—

Mean ± standard deviation ( = 4).
^bTabulated value of at confidence limit of 95% and three degrees of freedom, 3.18.