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International Journal of Analytical Chemistry
Volume 2015 (2015), Article ID 796249, 11 pages
http://dx.doi.org/10.1155/2015/796249
Research Article

Sample Preparation and Extraction in Small Sample Volumes Suitable for Pediatric Clinical Studies: Challenges, Advances, and Experiences of a Bioanalytical HPLC-MS/MS Method Validation Using Enalapril and Enalaprilat

Institute of Clinical Pharmacy and Pharmacotherapy, Heinrich-Heine-University, 40225 Düsseldorf, Germany

Received 31 October 2014; Revised 5 February 2015; Accepted 5 February 2015

Academic Editor: Mohamed Abdel-Rehim

Copyright © 2015 Bjoern B. Burckhardt and Stephanie Laeer. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Bjoern B. Burckhardt and Stephanie Laeer, “Sample Preparation and Extraction in Small Sample Volumes Suitable for Pediatric Clinical Studies: Challenges, Advances, and Experiences of a Bioanalytical HPLC-MS/MS Method Validation Using Enalapril and Enalaprilat,” International Journal of Analytical Chemistry, vol. 2015, Article ID 796249, 11 pages, 2015. doi:10.1155/2015/796249