The Application of a Desktop NMR Spectrometer in Drug Analysis

Table 1

¹H NMR data for morphine, heroin, 3OM, 6OM, codeine, and ACD in 0.5 mL D₂O.

Atom	Morphine	Heroin	3OM	6OM	Codeine	ACD
H1	6.71, d	6.90, d	6.85, d	6.74, d	6.80, d	6.84, d
H2	6.79, d	6.99, d	6.97, d	6.82, d	6.93	6.94, d
H5	5.09, d	5.31, d	5.14, d	5.24, d	5.10, d	5.30, d
H6	4.20, d	5.34, d	4.42, d	5.30, m	4.40, d	5.32, d
H7	5.76, d	5.62, d	5.78, d	5.58, d	5.76, d	5.75, d
H8	5.41, d	5.77, d	5.44, d	5.77, d	5.42, d	5.60, d
H9	4.24, s	4.28, s	4.26, s	4.20, s	4.25, s	4.25, s
H10	2.95,3.31, d	3.04,3.39, s	3.04,3.36, m	2.98,3.25, d	3.40,2.96, d	3.04,3.32, s
H14	3.02, s	3.18, s	3.04, m	3.14, s	3.02, s	3.15, s
H15	2.36,2.15, d	2.36,2.17, s	2.21,2.39, m	2.13,2.36, m	2.16, 2.37, d	2.10,2.36, d
H16	3.40,3.10, d	3.04,3.39, s	3.17,3.35, m	3.38,3.08, m	3.10,3.41, s	3.37,3.04, m
H17	3.02, s	3.04, s	3.04, s	3.04, s	3.02, s	3.04, s
H18	N/A	N/A	N/A	N/A	3.87, s	3.87, s
H19	N/A	2.17, s	2.36, s	2.20, s	N/A	N/A
H20	N/A	N/A	N/A	N/A	N/A	2.19, s
H21	N/A	2.36, s	N/A	N/A	N/A	N/A