Development of a Robust UPLC Method for Simultaneous Determination of a Novel Combination of Sofosbuvir and Daclatasvir in Human Plasma:<i> Clinical Application to Therapeutic Drug Monitoring</i>

<table class="fixed-width table-group" id="tab1"><tr><td><table class="table"><colgroup><col style="width:14.28em"/><col style="width:3.29em"/><col style="width:3.57em"/></colgroup><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Prepared QC samples (ng.mL<sup>−1</sup>)</td><td class="align_center">SF</td><td class="align_center">DC</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">LLOQ</td><td class="align_center">25</td><td class="align_center">50</td></tr><tr><td class="align_left">QL</td><td class="align_center">50</td><td class="align_center">100</td></tr><tr><td class="align_left">QM</td><td class="align_center">400</td><td class="align_center">1600</td></tr><tr><td class="align_left">QH</td><td class="align_center">3200</td><td class="align_center">6400</td></tr><tr><td class="align_left">ULOQ</td><td class="align_center">6400</td><td class="align_center">12800</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Quality control samples for SF and DC.</div>

International Journal of Analytical Chemistry

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Table 1

Table 1: Development of a Robust UPLC Method for Simultaneous Determination of a Novel Combination of Sofosbuvir and Daclatasvir in Human Plasma:<i> Clinical Application to Therapeutic Drug Monitoring</i> 

Table 1 | Development of a Robust UPLC Method for Simultaneous Determination of a Novel Combination of Sofosbuvir and Daclatasvir in Human Plasma: Clinical Application to Therapeutic Drug Monitoring 