Simultaneous Determination of Seven Active Components in Rat Plasma by UHPLC-MS/MS and Application to a Quantitative Study after Oral Administration of Huang-Lian Jie-Du Decoction in High Fat-Induced Atherosclerosis Rats

Table 2

Regression data and LLOQs of the multi-components determined in HLJDD.

Analyte	Linear range; (ng/mL)	Linear regression equations	Correlation coefficient ()	LLOQs; (ng/mL)
Baicalin	2.1-2625	y =35.46x+1561	0.9995	2.1
Baicalein	2.0-1750	y=2.522x+233.2	0.9989	2.0
Wogonoside	2.0-1875	y=669.6.x+55174	0.9949	2.0
Wogonin	2.0-136.7	y=5885x+30206	0.9985	2.0
Berberine	0.25-78.13	y=28947x+29485	0.9989	0.25
Palmatine	0.25-56.64	y=4786x+1293	0.9955	0.25
Jatrorrhizine	0.25-25.0	y =2877x+2720	0.9975	0.25