Research Article

Simultaneous Determination of Seven Active Components in Rat Plasma by UHPLC-MS/MS and Application to a Quantitative Study after Oral Administration of Huang-Lian Jie-Du Decoction in High Fat-Induced Atherosclerosis Rats

Table 6

The concentration of seven analytes in rat plasma after oral administration of three dosages of HLJDD.

AnalyteGroupsConcentration
(ng/mL)

BaicalinL262.95 ± 4.75
M489.06 ± 7.29
H1159.32 ± 126.39

BaicaleinL406.48 ± 62.62
M804.98 ± 104.02
H1885.93 ± 143.94

WogonosideL690.56 ± 4.33
M1542.70 ± 165.74
H4079.52 ± 21.00

WogoninL9.89 ± 9.76
M14.21 ± 8.17
H36.50 ± 15.72

BerberineL0.77 ± 0.19
M0.83 ± 0.19
H0.79 ± 0.34

PalmatineL15.75 ± 1.82
M27.73 ± 3.10
H25.64 ± 2.49

JatrorrhizineL0.18 ± 0.17
M0.39 ± 0.27
H0.03 ± 0.01