Research Article
A New Quinone Based Fluorescent Probe for High Sensitive and Selective Detection of Biothiols and Its Application in Living Cell Imaging
Table 1
Comparison of DDQ to other fluorescent probes for biothiols detection.
| | Probe | λex | λem | Detection limit | Response time | Reference |
| | A | 360 nm | 423 nm | 8.4 × 10−8 M for Cys
8.0 × 10−9 M for GSH | 30 min for Cys
15 min for GSH | [17] |
| | B | 400 nm | 530 nm | 5.0 × 10−7 M for Cys | 50 min for Cys | [18] |
| | CyR | 698 nm | 735 nm | 1.50 × 10−7 M for GSH | within 180 s for GSH | [19] |
| | DMDP-M | 385 nm | 470 nm | 1.80 × 10−7 M for Cys | 10 min for Cys | [20] |
| | C | 438 nm for Cys,
537 nm for GSH | 515 nm for Cys
567 nm for GSH | 1.1 × 10−7 M for Cys;
5.0 × 10−9 M for GSH | 10 min for Cys
120 s for GSH | [21] |
| | D | 450 nm | 545 nm | 3.5 × 10−8 M for Hcy
5.3 × 10−8 M for Cys
5.2 × 10−8 M for GSH | 20 s for Hcy,
Cys 5 min for GSH | [22] |
| | DDQ | 390 nm | 467 nm for Cys and Hcy;
494 nm for GSH | 2.17 × 10−9 M for Hcy
8.55 × 10−8 M for Cys
3.08 × 10−9 M for GSH | 33 min for Cys
20 min for Hcy
within 180 s for GSH | This work |
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