Research Article

Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-UV

Table 5

Linearity details of selected compounds.

CompoundEquationCorrelation coefficientF (Fisher)

Zol0.9982535.39
Nara0.9972057.85
Keto0.9972154.05
DHE0.9972121.47
Pizo0.9962325.35