A Validated RP-HPLC Stability Method for the Estimation of Chlorthalidone and Its Process-Related Impurities in an API and Tablet Formulation

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left" colspan="3">Gradient Programme: for blank solution, placebo solution, and sample solution</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">0.01</td><td class="align_center">100</td><td class="align_center">0</td></tr><tr><td class="align_left">16.0</td><td class="align_center">100</td><td class="align_center">0</td></tr><tr><td class="align_left">21.0</td><td class="align_center">0</td><td class="align_center">100</td></tr><tr><td class="align_left">50.0</td><td class="align_center">0</td><td class="align_center">100</td></tr><tr><td class="align_left">52.0</td><td class="align_center">100</td><td class="align_center">0</td></tr><tr><td class="align_left">60.0</td><td class="align_center">100</td><td class="align_center">0</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Mobile phase gradient elution programme.</div>

International Journal of Analytical Chemistry

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Table 2

Table 2: A Validated RP-HPLC Stability Method for the Estimation of Chlorthalidone and Its Process-Related Impurities in an API and Tablet Formulation 

Table 2 | A Validated RP-HPLC Stability Method for the Estimation of Chlorthalidone and Its Process-Related Impurities in an API and Tablet Formulation 