Research Article
Simultaneous Determination of 13 Constituents of Radix Polygoni Multiflori in Rat Plasma and Its Application in a Pharmacokinetic Study
Table 1
The optimized mass spectrometry parameters of the 13 constituents of RPM and IS.
| | Compound | Q1 mass (Da) | Q3 mass (Da) | DP (V) | CE (V) |
| | Chrysophanol | 253.0 | 225.1 | −98 | −37 | | Emodin | 269.0 | 241.0 | −60 | −36 | | Aloe-emodin | 269.1 | 240.1 | −100 | −31 | | Rhein | 283.0 | 256.1 | −60 | −35 | | Physcion | 283.3 | 240.1 | −60 | −35 | | Questin | 283.1 | 240.1 | −80 | −36 | | Citreorosein | 285.0 | 211.0 | −60 | −43 | | Questinol | 299.0 | 256.1 | −60 | −35 | | TSG | 405.0 | 311.0 | −80 | −25 | | TG | 407.0 | 245.0 | −60 | −23 | | CG | 415.0 | 253.0 | −60 | −20 | | EG | 431.1 | 269.0 | −120 | −120 | | PG | 445.0 | 283.0 | −80 | −17 | | Puerarin (IS) | 415.0 | 295.0 | −200 | −40 |
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