Pharmacokinetics of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, in Rats by UPLC-MS/MS

Figure 2

Representative UPLC-MS/MS chromatograms of lusutrombopag and poziotinib (IS). (a) Blank plasma; (b) blank plasma spiked with lusutrombopag (2 ng/mL)and IS (50 ng/mL); (c) a rat plasma sample taken 4 hours after the oral dose of 10 mg/kg lusutrombopag.

(a)

(b)

(c)