A Validated Liquid Chromatographic Method for Berberine Analysis in Tissue and Application

Table 4

Results of BB at a dose of 400 mg/kg in tissues of rat (mean ± SD, n = 6, µg/g).

Tissue	1 h		2 h		4 h
	With GA	Without GA	With GA	Without GA	With GA	Without GA
Liver	0.666 ± 0.142	0.629 ± 0.267	3.21 ± 1.92	2.08 ± 1.34	3.76 ± 2.73	2.42 ± 2.28
Spleen	0.049 ± 0.012	0.062 ± 0.019	0.183 ± 0.123	0.137 ± 0.109	0.349 ± 0.115	0.291 ± 0.110
Kidney	0.195 ± 0.134	0.189 ± 0.143	0.244 ± 0.120	0.267 ± 0.349	0.297 ± 0.155	0.202 ± 0.064