In the article titled “Quantitative Detection of miRNA-21 Expression in Tumor Cells and Tissues Based on Molecular Beacon” [1], the authors’ previous similar work on pre-miRNA-21 was not cited and discussed [2]. The authors said the two studies are similar in strategy, using a fluorescent probe to detect RNA, but with different probes and targets. With the structural differences of pre-miRNA and miRNA, they used a chimeric molecular beacon (the stem contains RNA bases) to detect pre-miRNA-21 in the earlier study [2], while they used a molecular beacon (entirely DNA bases) to directly detect miRNA-21 in the second article [1]. The studies were conducted at the same time and have similar outcomes, in that both LOD are 0.5 nM of the targets and there is a similar linear range (1–100 nM vs. 1–50 nM). The original version of Figure 3 that was replaced in an earlier corrigendum [3] was reproduced in error from Figure 2 in that earlier article.
Corrigendum | Open Access
Corrigendum #2 to “Quantitative Detection of miRNA-21 Expression in Tumor Cells and Tissues Based on Molecular Beacon”
Received05 Nov 2020
Accepted05 Nov 2020
Published15 Jan 2021
References
Q. Liu, J. Fan, C. Zhou et al., “Quantitative detection of miRNA-21 expression in tumor Cells and Tissues based on molecular beacon,” International Journal of Analytical Chemistry, vol. 2018, Article ID 3625823, 7 pages, 2018.
View at: Publisher Site | Google ScholarH.-L. Xie, T.-T. Wu, Z.-H. Xie, J.-L. Fan, and C.-Y. Tong, “Quantitative detection of PremicroRNA-21 based on chimeric molecular beacon,” Chinese Journal of Analytical Chemistry, vol. 46, no. 7, pp. e1847–e1853, 2018.
View at: Publisher Site | Google ScholarQ. Liu, J. Fan, C. Zhou et al., “Corrigendum to “quantitative detection of miRNA-21 expression in tumor Cells and Tissues based on molecular beacon,” International Journal of Analytical Chemistry, vol. 2020, Article ID 1515794, 2 pages, 2020.
View at: Publisher Site | Google Scholar
Copyright
Copyright © 2021 Qingxin Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.