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International Journal of Alzheimer’s Disease
Volume 2009, Article ID 257403, 10 pages
Research Article

Evaluation of BACE1 Silencing in Cellular Models

1Department of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland
2Organ Development Research Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Central 4, 1-1-1 Higashi, Tsukuba Science City, 305-8562 Ibaraki, Japan

Received 6 March 2009; Revised 1 June 2009; Accepted 11 June 2009

Academic Editor: Brian Austen

Copyright © 2009 Malgorzata Sierant et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Malgorzata Sierant, Milena Sobczak, Magdalena Janicka, Alina Paduszynska, and Danuta Piotrzkowska, “Biological and physicochemical characterization of siRNAs modified with 2 ',2 '-difluoro-2 '-deoxycytidine (gemcitabine),” New Journal Of Chemistry, vol. 34, no. 5, pp. 918–924, 2010. View at Publisher · View at Google Scholar
  • Agnieszka Krakowiak, Roza Pecherzewska, Renata Kaczmarek, Agnieszka Tomaszewska, Barbara Nawrot, and Wojciech J. Stec, “Evaluation of influence of Ap(4)A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis,” Bioorganic & Medicinal Chemistry, vol. 19, no. 16, pp. 5053–5060, 2011. View at Publisher · View at Google Scholar
  • Malgorzata Sierant, Alina Paduszynska, Julia Kazmierczak-Baranska, Benedetta Nacmias, Sandro Sorbi, Silvia Bagnoli, Elzbieta Sochacka, and Barbara Nawrot, “Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference,” International Journal of Alzheimer's Disease, vol. 2011, pp. 1–14, 2011. View at Publisher · View at Google Scholar
  • Xianbin Yang, Malgorzata Sierant, Magdalena Janicka, Lukasz Peczek, Carlos Martinez, Tom Hassell, Na Li, Xin Li, Tianzhi Wang, and Barbara Nawrot, “Gene Silencing Activity of siRNA Molecules Containing Phosphorodithioate Substitutions,” ACS Chemical Biology, vol. 7, no. 7, pp. 1214–1220, 2012. View at Publisher · View at Google Scholar
  • Malgorzata Sierant, Xianbin Yang, and Barbara Nawrot, “SiRNA ANALOGS CONTAINING PHOSPHORODITHIOATE SUBSTITUTIONS,” Phosphorus, Sulfur, and Silicon and the Related Elements, pp. 121212114507007, 2012. View at Publisher · View at Google Scholar
  • Qin Hong, Xia Chi, Lei Yang, Min Zhang, Xiao-Qin Pan, Mei Guo, Li Fei, Mei-Ling Tong, Rong-Hua Chen, and Xi-Rong Guo, “Increased locomotor activity and non-selective attention and impaired learning ability in SD rats after lentiviral vector-mediated RNA interference of Homer 1a in the brain.,” International journal of medical sciences, vol. 10, no. 1, pp. 90–102, 2013. View at Publisher · View at Google Scholar
  • Zbigniew J. Lesnikowski, Slawomir Janczak, Alina Kwiatkowska, Milena Sobczak, Barbara Mikolajczyk, Agnieszka B. Olejniczak, Marek Sochacki, and Barbara Nawrot, “siRNAs Modified with Boron Cluster and Their Physicochemical and Biological Characterization,” Bioconjugate Chemistry, vol. 24, no. 6, pp. 1017–1026, 2013. View at Publisher · View at Google Scholar
  • Agnieszka Krakowiak, Roza Pawlowska, Beata Kocon-Rebowska, Rafal Dolot, and Wojciech J. Stec, “Interactions of cellular histidine triad nucleotide binding protein 1 with nucleosides 5 '-O-monophosphorothioate and their derivatives - Implication for desulfuration process in the cell,” Biochimica et Biophysica Acta-General Subjects, vol. 1840, no. 12, pp. 3357–3366, 2014. View at Publisher · View at Google Scholar
  • Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Milena Sobczak, Błażej Wojtczak, Sławomir Janczak, Zbigniew Leśnikowski, and Barbara Nawrot, “High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents,” Molecules, vol. 22, no. 9, pp. 1393, 2017. View at Publisher · View at Google Scholar