Research Article
Risk of Dementia Associated with Elevated Plasma Homocysteine in a Latin American Population
Table 1
Characteristics of the Maracaibo Aging Study population.
| | Characteristics | All | Demented | Not demented |
| | Population, no. (% females) | 2100 (67.0) | 169 (74.0) | 1931 (66.4) | | Age, mean (SD), y | 67.2 (9.0) | 77.8 | 66.3 (8.3) | | Illiteracy, (%) | 298/2100 (14.2) | 61/169 | 237/1931 (12.3) | | Education, mean (SD), y | 5.6 (4.0) | 3.2 | 5.8 (4.0) | | Hypercholesterolemia, (%) | 711/1553 (45.8) | 49/121 (40.5) | 662/1432 (46.2) | | Diabetes, (%) | 287/2099 (13.7) | 32/169 | 255/1930 (13.2) | | Current smoker, (%) | 350/2100 (16.7) | 20/169 (12.0) | 329/1931 (17.0 ) | | Hypertension, (%) | 1739/2100 (82.8) | 141/169 (83.4) | 1598/1931 (82.8) | | Stroke, (%) | 113/2099 (5.4) | 40/169 | 72/1930 (3.7) | | Hyperhomocysteinemia, (%) | 844/2100 (40.2) | 117/169 | 727/1931 (37.6) | | tHcy, mean (SD), mol/L | 14.2 (6.3) | 18.6 | 13.9 (6.0) | | Folate, mean (SD), (ng/ml) | 5.3 (2.9) | 4.8 | 5.3 (3.0) | | Vit B12, mean (SD), (pmol/ml) | 416.9 (335.0) | 426.3 (341.5) | 415.9 (334.5) | | APOE allele frequency | | | | | ApoE-2 | 0.046 | 0.035 | 0.047 | | ApoE-3 | 0.838 | 0.769 | 0.842 | | ApoE-4 | 0.116 | | 0.111 |
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; , between demented and not demented groups.
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